University of Twente Student Theses
Optimization of the Implican Colorectal Anastamotic Device
Oosterbroek, Bram (2024) Optimization of the Implican Colorectal Anastamotic Device.
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| Abstract: | The most common treatment for colon cancer is the surgical removal of the cancerous section, a procedure known as colectomy. To restore normal colon function, the colon must be reconnected to the rectum via colorectal anastomosis. This is typically done with circular staplers, which often result in anastomotic leakage (AL). AL can necessitate reoperation and prolong hospital stays. Compression anastomosis is an alternative that reduces AL incidence. Implican, a medical start-up, has developed two snap-fit compression rings for this purpose. These rings connect the colon to the rectum, aligning their submucosa layers to promote primary wound healing and reduce healing time to ten days. Implican also created the Implican Anastomotic Device to place the rings. Pre-clinical testing revealed technical insights for improvement, such as difficulty of initiating the cutting step and the need for user feedback during the procedure. Additionally, the production process required significant post-processing, and the device design did not yet meet Medical Device Regulations (MDR). A regulative improvement cycle was employed to address these issues, leading to design optimizations. Tests identified that initiating the cutting step was hindered by friction and deformation. Design changes to key components reduced friction and coupling force by 24%, and a feedback system was integrated. Production was optimized using a combination of selective laser melting (SLM) and milling techniques. Simulation tests validated the redesign, demonstrating successful procedures without the above functionality issues and indicating that the root cause of the issues were resolved. |
| Item Type: | Essay (Master) |
| Clients: | Implican, Groningen, The Netherlands |
| Faculty: | TNW: Science and Technology |
| Subject: | 52 mechanical engineering |
| Programme: | Biomedical Engineering MSc (66226) |
| Link to this item: | https://purl.utwente.nl/essays/100218 |
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