University of Twente Student Theses
The development of a patient specific CPAP mask to optimize treatment for OSA patients.
Willemen, M.C.C. (2024) The development of a patient specific CPAP mask to optimize treatment for OSA patients.
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| Abstract: | Globally, over 400 million adults suffer from moderate to severe obstructive sleep apnea (OSA), a condition where the upper airway repeatedly narrows or collapses during sleep, causing partial or complete breathing stops. Continuous positive airway pressure (CPAP) is the gold standard for OSA treatment, using pressurized air delivered through a mask to keep the airway open. However, poor mask fit is a significant issue, leading to substantial air leakage and pressure points. This study aims to tackle these problems by developing patient-specific CPAP masks using 3D imaging and 3D printing techniques. A thorough stakeholder analysis guided the design, focusing on minimizing air leakage around the nose and eyes and preventing nasal pressure points. Using 3D stereophotogrammetry, a 3D scan of a mannequin head as well as 17 facial landmarks were obtained. These landmarks were used in parametric modeling to create a custom base curve for the mask, tailored to individual facial features. Two prototypes of patient-specific full-face CPAP masks were created using 3D printing and silicone molding techniques. The masks were validated for air leakage using a CPAP device and for face pressure using FSR sensors. Results showed that Prototype 2 significantly reduced air leakage, especially around the nasal area, compared to commercial masks. Additionally, the mask appeared to prevent pressure points in the nasal region, although further validation is necessary. This study demonstrates promising results for optimizing OSA treatment with patient-specific CPAP masks. Further research is needed to refine the mask cushion design and enhance validation experiments for facial pressure analysis. |
| Item Type: | Essay (Master) |
| Clients: | Medisch Spectrum Twente, Enschede, The Netherlands Medisch Spectrum Twente, Enschede, The Netherlands |
| Faculty: | TNW: Science and Technology |
| Subject: | 44 medicine, 50 technical science in general |
| Programme: | Biomedical Engineering MSc (66226) |
| Link to this item: | https://purl.utwente.nl/essays/100474 |
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