University of Twente Student Theses

Login

Soft-tissue tuning in a personalized musculoskeletal knee model using quantitative comparison between simulated and intraoperatively measured knee laxity

Matser, Iris (2022) Soft-tissue tuning in a personalized musculoskeletal knee model using quantitative comparison between simulated and intraoperatively measured knee laxity.

[img] PDF
5MB
Abstract:Pre-operative planning of robotic assisted total knee arthroplasty (RA-TKA may benefit from the use of a patient-specific musculoskeletal (MS) model. However, it is difficult to personalize the soft tissue properties in an MS model. In this study, the ability to personalize the reference strain of the ligaments in a previously developed knee-only MS model was evaluated. Of a patient who underwent RA-TKA, intraoperative varus and valgus laxity tests were performed, and the resulting lateral and medial joint gaps were measured. The sensitivity of the simulated joint gaps in a CT-based personalized model to changes in the ligament reference strains was then determined. Then, the modeled reference strains were manually tuned to replicate the intraoperatively measured joint gaps, which resulted in a simulated joint gap of 22.04 mm medially and 22.99 mm laterally. This means that the differences between the simulated and measured joint gaps decreased from 1.50 mm to -0.04 mm medially and from 1.11 mm to 0.01 mm laterally. However, it was difficult to assess the accuracy of the resulting simulated joint gaps due to an unknown intraoperatively applied force, model shifting, and high ligament strains. Automated optimization may contribute to a more accurate tuning process.
Item Type:Essay (Master)
Faculty:ET: Engineering Technology
Subject:30 exact sciences in general, 44 medicine, 50 technical science in general
Programme:Biomedical Engineering MSc (66226)
Link to this item:https://purl.utwente.nl/essays/100596
Export this item as:BibTeX
EndNote
HTML Citation
Reference Manager

 

Repository Staff Only: item control page