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Characterisation of holmium-165 micro-spheres in low-field MRI

Jongh, Luuc de (2024) Characterisation of holmium-165 micro-spheres in low-field MRI.

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Abstract:Holmium (Ho) micro-spheres can be imaged in trans-arterial radio-embolisation (TARE) us- ing magnetic resonance imaging (MRI). MRI offers many benefits compared to conventional imaging techniques used in TARE. In previous studies this has been extensively researched using high-field MRI systems of 1.5T and 3T. However, low-field MRI can offer certain advantages over high-field MRI for TARE. To investigate the possibility of using low-field MRI in TARE, holmium micro-spheres are tested in low-field MRI using a 0.5T MRI scanner. Using phantoms containing a range of holmium micro-sphere concentrations, relaxivity r∗2 has been determined at 0.5T 1.5T and 3T. The results at 0.5T show that holmium-microspheres have a significant contrast effect, opening up possibilities for further research into the use of low-field MRI in Ho-TARE.
Item Type:Essay (Bachelor)
Faculty:TNW: Science and Technology
Subject:44 medicine, 50 technical science in general
Programme:Biomedical Technology BSc (56226)
Link to this item:https://purl.utwente.nl/essays/101739
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