University of Twente Student Theses
As of Friday, 8 August 2025, the current Student Theses repository is no longer available for thesis uploads. A new Student Theses repository will be available starting Friday, 15 August 2025.
Motion Control of Biohybrid Microrobot Clusters in Cerebral Arteries Using X-ray-Guided Magnetic Fields
Schrier, T.P. (2024) Motion Control of Biohybrid Microrobot Clusters in Cerebral Arteries Using X-ray-Guided Magnetic Fields.
|
PDF
4MB |
| Abstract: | In recent years, brain aneurysms have been diagnosed in 1% to 5% of the adult population, with ruptures often leading to fatal strokes. Current treatments, such as surgical clipping and endovascular coiling, are considered highly invasive, with damage to tissues as a result. A promising alternative involves using magnetic microrobots, which offer a minimally invasive approach. These microrobots can be directed toward the aneurysm to occlude blood flow and prevent aneurysm growth. However, precise wireless motion control within the complex and tortuous arteries of the human brain remains a challenge. This paper investigates the feasibility of guiding tetherless biohybrid microrobot clusters into unruptured intracranial aneurysms using a rotating magnetic field. Motion control experiments demonstrate that clusters of nanoparticle-coated sperm cells can be successfully directed into intracranial aneurysms, achieving an average path accuracy of 99.12% when navigating from the intersection of the right common carotid artery and external carotid artery toward the aneurysm and an average path accuracy of 96.24% when navigating from the intersection of the left common carotid artery and external carotid artery toward the aneurysm. These findings suggest that biohybrid microrobot clusters have significant potential in the prevention of brain aneurysms. |
| Item Type: | Essay (Bachelor) |
| Faculty: | TNW: Science and Technology |
| Subject: | 50 technical science in general |
| Programme: | Biomedical Technology BSc (56226) |
| Link to this item: | https://purl.utwente.nl/essays/101792 |
| Export this item as: | BibTeX EndNote HTML Citation Reference Manager |
Show download statistics for this publication
Show download statistics for this publicationRepository Staff Only: item control page