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Towards at-home monitoring of aortic valve stenosis : The effect of aortic valve stenosis on the photoplethysmography signal obtained at the wrist

Pol, L.R. (2025) Towards at-home monitoring of aortic valve stenosis : The effect of aortic valve stenosis on the photoplethysmography signal obtained at the wrist.

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Embargo date:1 January 2028
Abstract:Introduction: Aortic valve stenosis (AS) requires frequent monitoring. Photoplethysmography (PPG) is a cheap, easy technique that might be used for monitoring of AS. The aim of this thesis was to explore the effects of AS on the PPG signal. Methods: Patients wore a wristband with PPG sensor. First, we determined requirements for reliable waveform analysis. The performance of a heartbeat selection and landmark detection algorithm was tested by comparing it to manually annotated heartbeats. Next, the minimum number of heartbeats required for waveform analysis was determined. Second, we compared PPG features from patients with no/mild AS and patients with moderate/severe AS. The PPG features were used in several classification models. Results: The landmark detection algorithm could locate the systolic peak and dicrotic notch reliably, but not the diastolic peak. For reliable waveform 138 heartbeats were required. Several PPG features differed between patients without AS (n=223) and patients with AS (n=259). The
Item Type:Essay (Master)
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Technical Medicine MSc (60033)
Link to this item:https://purl.utwente.nl/essays/104994
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