University of Twente Student Theses
Development of a protocol for the imaging and diameter analysis of the common femoral vein in a tiltable MRI
Cordes, L.J.C. (2025) Development of a protocol for the imaging and diameter analysis of the common femoral vein in a tiltable MRI.
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| Abstract: | Diameter measurements of (the iliofemoral) veins are sensitive to cross-sectional crush [1] and body position [2]. The diameter of a vein is of importance for the placement of venous stents in the treatment of iliofemoral Deep Vein Thrombosis (DVT). This research therefore investigated the development of an image acquisition protocol in a tiltable MRI to image the left common femoral vein (LCFV) in upright, supine, and hip flexion positions and a method for subsequent diameter analysis of the LCFV in these positions. Multiple Magnetic Resonance Imaging (MRI) sequences were experimented with, with the sequences with the best initial results further optimized by variation of MRI parameters. For diameter analysis, the Maximum-Inscribed-Sphere (MIS) and Circular-Equivalent (CE) diameter offered by ’3D Slicer’ could be used. The resulting image acquisition protocol comprises a T2 Fast Spin Echo (FSE) sequence for a good overview of pelvic anatomy and a Time-Of-Flight (TOF) sequence for the subsequent analysis of the diameter of the LCFV. When comparing the LCFV in upright and supine positions, the acquired MRI images show that the LCFV has become twice as large. The CE diameter (upright) has increased to a range of approximately 9.2 - 15.2 mm and the MIS diameter to a range of approximately 7.6 - 12.0 mm compared to a range of 3.0 - 10.8 mm (CE, supine) and 2.5 - 8.8 mm (MIS, supine). When comparing the LCFV in hip-flexion and supine positions, the acquired MRI images show that the LCFV has become 1,5 times larger. The CE diameter has grown to a range of approximately 7.5 - 13.2 mm (hip-flexion) and the MIS diameter to a range of 5.8 - 9.5 mm compared to the above mentioned ranges for the supine position. The image quality from the upright scan implicated the diameter measurements in ’3D Slicer’ as the threshold value could not be set such that only the vein would be selected. It is suggested to investigate a way to reduce motion from the participant in upright position. Furthermore, flow-related ghosting artefacts presented with the TOF sequence and may also affect the diameter measurements. The Circular-Equivalent (CE) diameter is recommended for diameter measurement with the goal of stent placement. |
| Item Type: | Essay (Bachelor) |
| Faculty: | TNW: Science and Technology |
| Subject: | 33 physics, 42 biology, 44 medicine |
| Programme: | Biomedical Technology BSc (56226) |
| Link to this item: | https://purl.utwente.nl/essays/106205 |
| Export this item as: | BibTeX EndNote HTML Citation Reference Manager |
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