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Quantification of postoperative atrial fibrillation by automatic analysis of electrocardiograms. A study to find incidence and burden of PoAF after open chest surgical aortic valve replacement.

Boonstra, M.J. and Leeuwen, K.G. van and Porte, F.M. and Spijkerboer, F.L. (2015) Quantification of postoperative atrial fibrillation by automatic analysis of electrocardiograms. A study to find incidence and burden of PoAF after open chest surgical aortic valve replacement.

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Abstract:In this study a method has been developed for automatic postoperative atrial fibrillation (PoAF) detection, which has been used to examine the episode incidence and burden and the relation between these variables for patients suffering from new-onset PoAF in the five days after open chest surgical aortic valve replacement. A combination of an algorithm for R-peak detection and an AF detection function made by Applied Biomedical Systems BV was used to enable automatic AF detection for episodes of minimally 30 seconds. For the population (n=18) with a total registration time of 1590 hours the weighted mean incidence per 24 hours was 12.73(±12.98) and the weighted mean burden ratio 0.105 (±0.168) within the six days after surgery. The second postoperative day shows the highest episode incidence, though insignificant. The burden remains fairly constant from the second until the fifth postoperative day. No correlation is observed between incidence and burden. As longer episodes have a different effect on severity of PoAF and prognosis, the burden might be a new indicator for this. Further research could focus on investigating a larger population,variation in episode length and correlation between PoAF episodes and hemodynamic factors.
Item Type:Essay (Bachelor)
Clients:
Erasmus Medical Centre, Rotterdam, The Netherlands
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Technical Medicine BSc (50033)
Link to this item:http://purl.utwente.nl/essays/67252
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