University of Twente Student Theses


Nano-bio-sensing with CMOS-Nano-capacitor-array

Boer, Vincent de (2015) Nano-bio-sensing with CMOS-Nano-capacitor-array.

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Abstract:In this report the process of detecting of 28 nm polystyrene beads andCCMV(Cowpea Chlorotic Mottle Virus) binding-events with a CMOS nano capacitor array from NXP are described. The purpose of this bachelor assignment is to find the limits of the CMOS nano capacitor array. To help with the data processing a filter-program was made during this bachelor assignment to filter the data of each experiment down to a manageable size. We were successfully able to detect 28 nm polystyrene beads binding-event, however the CCMV binding-events were much harder to detect and were only reliably detected by looking at the average binding rate of the entire array (or at least a portion of it). The AFM was used to confirm the binding-events detected by the CMOS-chip.
Item Type:Essay (Bachelor)
Faculty:TNW: Science and Technology
Subject:50 technical science in general
Programme:Advanced Technology BSc (50002)
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