University of Twente Student Theses
Technical and clinical analysis of ULDCT : Technical analysis and potential added clinical value of Ultra-Low Dose Computed Tomography compared to chest X-ray
Velden, L.L. van der (2017) Technical and clinical analysis of ULDCT : Technical analysis and potential added clinical value of Ultra-Low Dose Computed Tomography compared to chest X-ray.
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| Abstract: | PURPOSE: The goal of this study is to technically evaluate and to determine the added clinical value of Ultra-Low Dose Computed Tomography (ULDCT) for detecting chest pathology in clinical practise compared to routine Chest X-Ray (CXR). MATERIALS AND METHODS: 50 patients underwent in addition to CXR an ULDCT (120-135 kV, 10 mA, pitch 1.388:1, 0.3-s rotation time). The CT scans were reconstructed with IR reconstructions (Adaptive Dose Reduction 3D (AIDR3D) and Forward projected model-based Iterative Reconstruction SoluTion (FIRST), Toshiba Medical Systems, Otawara, Japan). All images were evaluated by two expert radiologists and scored with the use of scoring forms. For 10 patients quantitative parameters were measured to assess differences between the two reconstruction techniques. RESULTS: All ULDCT were qualified as being of diagnostic quality by the radiologists. Significant differences were detected between the two modalities, with a higher sensitivity of 10% for the detection of pulmonary pathology for ULDCT compared with CXR. For eight (16%) patients the ULDCT had a clinical added value by changing their treatment policy. The effective dose of ULDCT (0.071±0.007 mSv) was only slightly higher compared to CXR (0.040±0.018 mSv, p<0.05). FIRST CT reconstructions showed noise reduction in the 5 mm slice reconstructions techniques, but did not have added clinical value compared to AIDR3D. CONCLUSION: An ULDCT with comparable dose to CXR is more sensitive to detect chest pathology and may be used in clinical practise. |
| Item Type: | Essay (Master) |
| Faculty: | TNW: Science and Technology |
| Subject: | 44 medicine |
| Programme: | Technical Medicine MSc (60033) |
| Link to this item: | https://purl.utwente.nl/essays/71789 |
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