University of Twente Student Theses
On-Chip HPLC analysis of drugs of abuse - Analysis of cocaine, morphine and their metabolites using an on-chip HPLC system.
Hilgerink, T. (2016) On-Chip HPLC analysis of drugs of abuse - Analysis of cocaine, morphine and their metabolites using an on-chip HPLC system.
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| Abstract: | Being able to analyse drugs of abuse in blood at a crime scene can save a lot of time and money. Lab-on-a-chip devices could possibly be used to achieve this goal. A microchip based HPLC system coupled to UV-Vis has been used to developed a method for simultaneous measurements of cocaine, benzoylecgonine, morphine and morphine-3ß-D-glucorinide in water. Methods to prepare blood for on-chip analyses are also discussed in this thesis. The research showed concentrations of 12.5 mg/L could be measured, with a high possibility of being able to measure much lower concentrations as well. |
| Item Type: | Essay (Master) |
| Faculty: | TNW: Science and Technology |
| Subject: | 35 chemistry |
| Programme: | Science Education and Communication MSc (60708) |
| Link to this item: | https://purl.utwente.nl/essays/71895 |
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