University of Twente Student Theses


Visualizing neural circuits with concurrent TMS-fMRI

Vink, J.J.T. (2017) Visualizing neural circuits with concurrent TMS-fMRI.

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Abstract:Major depressive disorder (MDD) is a highly complex disorder that severely affects mood and pleasure in everyday activities. Its complexity appears through its diverse manifestations and its treatment resistant nature. Importantly, MDD is one of the leading causes of disability and the most prevalent mental disorder worldwide. In the first chapter, we show that MDD is associated with a specific dysfunctional brain network and that a response to treatment correlates with normalization of dysfunctional regions within this network. We shed some light on the role of individual regions brain in the pathology of MDD and we relate the complexity of the dysfunctional network to the diverse and treatment resistant nature of MDD.
Item Type:Essay (Master)
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Technical Medicine MSc (60033)
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