The health economic impact of (mis)classifying pregnant women with Gestational Diabetes Mellitus : the incremental cost-effectiveness of the use of an alternative testing strategy in pregnant women with (suspected) Gestational Diabetes Mellitus compared to the routine laboratory strategy.

Vollenbroek, Aniek N. (2017) The health economic impact of (mis)classifying pregnant women with Gestational Diabetes Mellitus : the incremental cost-effectiveness of the use of an alternative testing strategy in pregnant women with (suspected) Gestational Diabetes Mellitus compared to the routine laboratory strategy.

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Abstract:Gestational Diabetes Mellitus (GDM) is defined as Diabetes Mellitus (DM) diagnosed in the second or third trimester of pregnancy that is not clearly either type I or type II DM, while pregnant women in the first trimester are classified as type II DM due to the ongoing epidemic of obesity. GDM is the most common form of metabolic disorders during pregnancy and its prevalence is around 5%, which is increasing due to advanced maternal age and obesity. GDM can cause serious complications for both mother and child. Therefore an appropriate diagnostic process is important to avoid or minimize the complications for both mother and child during pregnancy, at delivery and in the long-term. The Oral Glucose Tolerance Test (OGTT) is used in the diagnostic process to correctly diagnose GDM, but currently the laboratory strategy to perform the OGTT is not optimal due to the degradation of glucose by the glycolysis in vitro. Consequently, alternative testing strategies were examined. In this study, the Cost-Effectiveness of the optimal laboratory strategy, the use of a NaF-EDTA-Citrate tube and Point Of Care (POC) testing, as compared to the routine laboratory strategy was estimated for pregnant women with (suspected) GDM using a health economic model.
Item Type:Essay (Master)
Clients:
Amphia Hospital, Breda, The Netherlands
Amphia Hospital, Breda, The Netherlands
Faculty:TNW: Science and Technology
Subject:42 biology, 44 medicine, 85 business administration, organizational science
Programme:Health Sciences MSc (66851)
Link to this item:http://purl.utwente.nl/essays/72456
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