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Temperature optimization of the SuperParamagnetic Quantifier for comparison with standard methods

Schlief, J.G.L. (2017) Temperature optimization of the SuperParamagnetic Quantifier for comparison with standard methods.

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Abstract:For use in sentinel lymph node biopsies, a hand held probe has been developed to detect superparamagnetic nanoparticles using Differential magnetometry. The SuperParamagnetic Quantifier (SPaQ) is designed to find suitable particles to be used with the hand held probe. Additionally, it can quantify the amount of nanoparticles in a sample. The system’s temperature dependency is determined to compare it to Vibrating Sample Magnetometry(VSM) and Magnetic Particle Spectroscopy (MPS). Measurements with the system in thermal equilibrium return a constant dM/dH curve where some drift occurs. For this drift is corrected using a fit of the Langevin function. The VSM determines the static magnetization curve, as little relaxation occurs. MPS results in the dynamic dM/dH curve, dependent on the used field amplitude and frequency. SPaQ’s output curves could be considered a hybrid of a dynamic and a static dM/dH curve. Thus resulting in the conclusion that SPaQis most suitable for its intended purpose.
Item Type:Essay (Bachelor)
Faculty:TNW: Science and Technology
Subject:30 exact sciences in general, 50 technical science in general
Programme:Advanced Technology BSc (50002)
Link to this item:https://purl.utwente.nl/essays/72900
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