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A semi-anthropmorphic photoacoustic breast phantom

Dommelen, R.C. van (2018) A semi-anthropmorphic photoacoustic breast phantom.

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Abstract:Anthropomorphic breast phantoms are needed to validate and improve photoacoustic imaging systems for breast cancer detection. A first step to achieve this is by fabricating a semi-anthropomorphic photoaoustic breast phantom, having less complex than but comparable structures to tissue. In order to do this, first the acoustic and optical properties of the breast tissues fat, fibroglandular, skin and blood vessels were obtained from literature. Then an inventarisation of available materials and fabrication techniques to mimic these tissue types was done. By scoring these available materials on a set of requirements, three candidate materials for mimicking breast tissue were remaining. These materials were acoustically characterised, which resulted in custom poly (vinyl chloride)plastisol (PVCP) to be most suitable as phantom material for this application. The breast phantom was developed using 3D printed moulds. The phantom consists of a silicone skin outer layer, a fat layer and a fibroglandular region in the center. The irregular boundary between fat and fibroglandular tissue mimicking materials (TMM) is based on a 3D model of a cauliflower. Two tumors and a blood vessel were inserted in the phantom. Fat, fibroglandular and tumor/blood TMM were all fabricated using different compositions of PVCP.
Item Type:Essay (Master)
Faculty:TNW: Science and Technology
Subject:33 physics, 44 medicine, 50 technical science in general
Programme:Biomedical Engineering MSc (66226)
Link to this item:http://purl.utwente.nl/essays/75909
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