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Evaluation of Motion Control Algorithms for Miniaturized Agents Moving Inside 3D Fluidic Microchannels

Niehoff, Dennis (2018) Evaluation of Motion Control Algorithms for Miniaturized Agents Moving Inside 3D Fluidic Microchannels.

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Abstract:The clinical application of drug-carrying microagents requires their control in 3D based on position feedback provided by imaging modalities such as ultrasound imaging. This work demonstrates the functionality of the different aspects going into the wireless control of microspheres. These include production of microchannels, equipment of microspheres with adequate substances, tracking of the microagent in 3D with a 2D ultrasound probe and a proposed control structure to determine the forces to be exerted onto the microagent by an external magnetic field. The control structure is tested in simulations and the microsphere is tracked initially in a steady position, then in a simple vertical microchannel and finally a curved 3D microchannel. The measurement results suggest that the developed tracking algorithm is suitable for this application and allows the setup to track the microsphere with a diameter of 1 mm inside of variable-sized, fluidic microchannels.
Item Type:Essay (Master)
Faculty:ET: Engineering Technology
Subject:33 physics, 50 technical science in general, 52 mechanical engineering, 53 electrotechnology, 54 computer science
Programme:Systems and Control MSc (60359)
Link to this item:http://purl.utwente.nl/essays/76886
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