University of Twente Student Theses


Breast cancer diagnostics in daily practice: the place of PAMMOTH

Voets, M.M (2018) Breast cancer diagnostics in daily practice: the place of PAMMOTH.

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Abstract:With incidence numbers still rising, breast cancer is the leading cancer diagnosis in women worldwide. Therefore, early detection and precise diagnosis of breast cancer is an important factor contributing to accurate therapy and better survival chances. The goal of this study is to outline the hospital-based diagnostic care pathway of patients with suspected breast cancer in the Netherlands and to identify features which influence the diagnostic pathway. Two different databases have been analysed; one ’benign’ database containing approximately 31,000 patients with suspected breast cancer, and one ’malignant’ database containing approximately 2,200 diagnosed breast cancer pa- tients. Information in the malignant database originates from the Netherlands Cancer Registry (NCR) and hospital-based financial data, accommodated by Performation. Information in the benign database was based on financial data only. Both databases have been carefully evaluated to reveal variation between and patterns within the diagnostic care pathways. In- fluencing features on the diagnosis of breast cancer, days until diagnosis and number of diagnostic care activities have been identified in the malignant diagnostic care pathway, using the Lasso method and cross-validation together with Cox and Poisson regression models.
Item Type:Essay (Master)
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Health Sciences MSc (66851)
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