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Detection of central sensitization in chronic pain patients visiting the outpatient pain clinic of St. Antonius Hospital

Petter, L. (2018) Detection of central sensitization in chronic pain patients visiting the outpatient pain clinic of St. Antonius Hospital.

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Abstract:In the Netherlands, 18% of the adults suffer from chronic pain. Detection of central sensitization would provide information about the patients nociceptive system that could enable mechanism-based therapy. The aim of this thesis was to set-up a process for the outpatient pain clinic in St. Antonius Hospital for the detection of central sensitization in chronic pain patients with electrical Quantitative Sensory Testing (eQST). The preliminary results did not show significant differences in pain threshold for chronic low back patients compared to healthy controls (t(95)=-0.131, p=0.896). The CSI score did show a significant difference between the two populations (t(95)=5.395, p<0.001). Regarding of the baseline characteristics, only gender seemed to be an influence related to the pain threshold. This thesis offers a clinical process aligned with current clinical practice at the outpatient pain clinic to eventually detect and monitor central sensitization. The monitoring process has successfully been implemented at St. Antonius Hospital. So far, no differences between CLBP and healthy controls in pain threshold were found, however still too few pain patients have been included. Subsequently, it is too early to draw conclusions from these preliminary results. Thereby is recommended to include more patients to evaluate the monitoring process of central sensitization.
Item Type:Essay (Master)
Clients:
St. Antonius Hospital, Nieuwegein, Netherlands
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Technical Medicine MSc (60033)
Link to this item:http://purl.utwente.nl/essays/76952
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