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In vivo measurements of human tongue elasticity using a volume-based aspiration method : towards a personalized biomechanical tongue model

Boonstra, Sander (2019) In vivo measurements of human tongue elasticity using a volume-based aspiration method : towards a personalized biomechanical tongue model.

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Abstract:The Virtual Therapy project wants to develop a biomechanical tongue model to simulate different treatment options and predict the functional outcome after head and neck cancer. A cohort with 16 healthy volunteers was studied to estimate the elastic properties of the human tongue using an in vivo measurement technique. A volume-based aspiration method for in-vivo mechanical characterization of soft tissue, called LASTIC, was used. An inverse Finite Element Analysis of the aspiration experiment using the Gent hyperelastic material model provided the Young’s modulus. The Gent model contains two parameters, the Young’s modulus and a strain limiting factor. An overall mean Young’s modulus of 4.8±1.73 kPa was found. For the dimensionless parameter we found an average value of 0.32±0.11. We found a good reproducibility within each subject with an Intra Class Correlation of 0.78. The results presented in this report gave a good estimation of the elastic behavior of tongue tissue. The method provided great insight in what the elastic response might be. The design of LASTIC and its ability to provide contrast between the mechanical local behavior of different materials, makes it a very promising and feasible technique to measure the elastic properties of the human tongue.
Item Type:Essay (Master)
Faculty:TNW: Science and Technology
Subject:02 science and culture in general, 33 physics, 42 biology, 44 medicine, 52 mechanical engineering
Programme:Technical Medicine MSc (60033)
Link to this item:http://purl.utwente.nl/essays/77051
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