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Microbiology of early infected arthroplasty after revision surgery: implications for the optimal empiric antibiotic.

Xykominos, D.S. (2019) Microbiology of early infected arthroplasty after revision surgery: implications for the optimal empiric antibiotic.

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Abstract:Periprosthetic Joint Infection (PJI) after total hip and knee arthroplasty is a serious and challenging complication for the patient, the surgeon and the healthcare system. Infection complicates 1 to 2% of the and an even higher proportion in revision surgery. In 2017 approximately 75,000 knee and hip primary and revision surgeries are performed in the Netherlands and it is anticipated to increase to 110,000 in 2030. Empiric administration of antibiotics treat and slow the PJI progression down when infection is suspected and the pathogens are unidentified. Early treatment is important to minimize morbidity and further complications. The current consensus in antibiotic administration for early PJI states the use of the same empiric antibiotics after revision surgery as in primary surgery. It is uncertain whether this approach provides the best care to patients who developed PJI after revision surgery, as it is uncertain what the efficacy of current empiric antibiotics is. The aim of this study is to evaluate the optimal empiric antibiotic treatment for early PJI after knee or hip revision surgery.
Item Type:Essay (Bachelor)
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Health Sciences BSc (56553)
Link to this item:http://purl.utwente.nl/essays/78312
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