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Use of upper airway measurements for the prediction of successful mandibular advancement device therapy both in protrusion and retraction of the mandible in patients with obstructive sleep apnoea

Buitenhuis, G.H. (2019) Use of upper airway measurements for the prediction of successful mandibular advancement device therapy both in protrusion and retraction of the mandible in patients with obstructive sleep apnoea.

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Abstract:Introduction: One of the treatments for obstructive sleep apnoea (OSA) is a mandibular advancement device (MAD). However, MAD therapy is only completely successful in around 48% of the patients. In this study, flow and resistance parameters obtained by the forced oscillation technique (FOT), negative expiratory pressure (NEP) and spirometry are investigated for the prediction of successful MAD therapy. Methods: 23 patients with OSA were included. Patients had an initial apnoea-hypopnoea index of ≥15 and have (had) a MAD therapy with optimal titration. Spirometry, FOT and NEP were performed in a supine position; with the mandible in a protruded and retracted position. Flow, pressure and resistance parameters were obtained. The differences in these parameters between the measurements with the mandible in a protruded and retracted position were used as predictive value for MAD success. Results: There were no significant differences in spirometry parameters between the MAD successful and non-successful group. Two parameters of the NEP and multiple parameters of the FOT differed significantly between the successful and non-successful group. Conclusion: None of the spirometry parameters are suitable as predictors for MAD success. Two parameters of the NEP and multiple of the FOT differed significantly between the MAD successful and non-successful group.
Item Type:Essay (Master)
Clients:
Medisch Spectrum Twente, Enschede, the Netherlands
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Technical Medicine MSc (60033)
Link to this item:http://purl.utwente.nl/essays/79238
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