University of Twente Student Theses


Gold nanoparticles for biosensing

Kaptein, J.A. (2020) Gold nanoparticles for biosensing.

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Abstract:Gold nanoparticles are increasingly used for biosensing purposes. This is because of the concept of localized surface plasmons which induces an enhancement in the electric near-field of gold nanoparticles and yields an oscillation of electrons in the visible range. In this case the purpose is early cancer detection, from urine, by looking at the red-shift of coupled gold nanoparticles. The scattering cross section and near-field enhancement of various shape size combinations is gathered and for shape size combinations that meet the requirements the scattering cross section upon coupling with nano spheres is gathered. Different distances from the spheres to the particles will be simulated. The simulations are done using the MNPBEM toolbox in MATLAB. This toolbox employs the boundary element method. The boundary method is a way of solving Maxwell equations only at the boundaries of particles which makes it fast in comparison to other toolboxes. It is found that multiple shape size combinations are valid for the purpose of this project, however a rod with a 60 nm diameter and a height of 100 nm is found to be the best suited since it shows a clear red-shift and has high peak wavelengths when both coupled and uncoupled. But most importantly it shows a strong near-field enhancement for the uncoupled particle.
Item Type:Essay (Bachelor)
Faculty:EEMCS: Electrical Engineering, Mathematics and Computer Science
Subject:30 exact sciences in general, 33 physics, 50 technical science in general, 53 electrotechnology
Programme:Electrical Engineering BSc (56953)
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