University of Twente Student Theses


Quality of life and functional outcome after different types of Total Mesorectal Excision in Dutch patients with rectal carcinoma

Bauhuis, J.G.J and Hulshof, I.M. (2020) Quality of life and functional outcome after different types of Total Mesorectal Excision in Dutch patients with rectal carcinoma.

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Abstract:Introduction: The interest in robot-assisted surgery as an alternative TME approach in rectal cancer has grown over the years. Although this technique is more expensive than the open or laparoscopic approach, advantage is expected in different outcomes. This is due to the magnification possibility and free movements during the procedure. However, the superiority of robotic surgery to laparoscopic surgery in the treatment of rectal cancer is still debated. This research described the quality of life and functional outcomes after robot-assisted TME for rectal cancer and compared them to the outcomes of the laparoscopic and transanal TME. Method: Three patient groups with a total of 101 patients were included in this study: 24 patients who underwent laparoscopic TME, 25 patients who underwent TaTME and 52 patients who underwent robot-assisted TME. All patients were asked to complete five questionnaires related to quality of life and function [EQ-5D-3L, EORTC-QLQ C30, EORTC-QLQ C29, Low Anterior Resection Syndrome score (LARS), and International Prostate Symptom Score IPSS]. In the robot-assisted group the female patients also filled in the FSFI questionnaire. Results: The EORTC-QLQ C30 and EQ-5D-3L questionnaires showed some significant differences in terms of index value and pain when comparing the laparoscopic and transanal group with the robot-assisted group. Outcomes of the LARS, EORTC-QLQ-29 and IPSS showed similar outcomes. Conclusion: There were no overall differences between the groups, although differences were seen in subscores. Therefore, the robot-assisted approach seems to be a reasonable alternative approach in the treatment of rectal cancer. However, the choice of the optimal approach depends on different factors and should be made per individual patient. Further research, which takes the limitations and recommendations of this study into account, is desired to confirm these results.
Item Type:Essay (Bachelor)
Rijnstate, Arnhem, Netherlands
Faculty:TNW: Science and Technology
Subject:42 biology
Programme:Health Sciences BSc (56553)
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