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Towards the introduction of magnetic resonance guided stereotactic body radiotherapy for the treatment of prostate cancer

Hamelink, I. (2020) Towards the introduction of magnetic resonance guided stereotactic body radiotherapy for the treatment of prostate cancer.

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Abstract:The main challenge in radiotherapy (RT) is ensuring that the dose to the surrounding tissue is kept as low as possible while delivering a relatively high dose to the tumor. Currently, the clinical introduction of magnetic resonance imaging (MRI) guided RT might enable more effective tumor targeting while sparing the surrounding tissue as much as possible. Especially treatment of prostate carcinoma might benefit from this, since accurate dose delivery is highly in uenced by interfractional motion and deformation of the prostate gland. Before introducing MR guided prostate RT within the clinical practice, it should be clear whether it actually leads to improved sparing of organs at risk (OAR) and target coverage compared to cone beam computed tomography (CBCT) guided prostate RT. The aim of this study is to quantify the (theoretical) clinical added value of the use of MR accelerator (e.g. MR-Linac) systems by comparing planning options for MRI guided RT versus CBCT guided RT for the treatment of prostate carcinoma.
Item Type:Essay (Master)
Faculty:TNW: Science and Technology
Subject:44 medicine, 50 technical science in general
Programme:Technical Medicine MSc (60033)
Link to this item:http://purl.utwente.nl/essays/84813
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