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Wireless Navigation for Tumor Localization and Resection Margin Assessment during Laparoscopic Rectal Cancer Surgery

Bolscher, BSc Wouter F. ten (2021) Wireless Navigation for Tumor Localization and Resection Margin Assessment during Laparoscopic Rectal Cancer Surgery.

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Full Text Status:Access to this publication is restricted
Embargo date:1 June 2024
Abstract:Laparoscopic rectal cancer surgery is associated with positive resection margin rates of 10-15%, while larger margins are shown to negatively impact functional outcome. Therefore, this indicates a need for accurate tumor localization and margin assessment during rectal cancer surgery. To this end, a new wireless surgical navigation setup is proposed, where preoperative imaging, showing relevant anatomy and the surgical target, is used intraoperatively to guide a surgeon using tracked surgical instruments. In this study, we investigate the safety, accuracy and usability of a wireless surgical navigation setup for real-time rectal tumor tracking in laparoscopic surgery. No signs of electromagnetic interference were found for our proposed navigation setup, while promising results are shown for transponder accuracy, with relative position and orientation accuracy below 1 mm and 1. Our novel wireless navigation setup is presented and intraoperative workflow and visualization has shown good usability and accuracy. Our preliminary work on three tissue specimen suggests relative stability of transponders when implanted in tumor tissue even in dynamic experiments. Therefore, the presented wireless navigation setup shows potential for use during rectal cancer surgery, aiming to reduce positive RM while sparing healthy tissue.
Item Type:Essay (Master)
Clients:
Antoni van Leeuwenhoek, Amsterdam, Netherlands
Faculty:TNW: Science and Technology
Subject:44 medicine, 50 technical science in general
Programme:Technical Medicine MSc (60033)
Link to this item:http://purl.utwente.nl/essays/86300
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