University of Twente Student Theses


Developing a Thyroid Phantom for Radiofrequency Ablation

Waard, j.j. de (2021) Developing a Thyroid Phantom for Radiofrequency Ablation.

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Abstract:Thyroid nodules are very common and have a prevalence of up to 67% in the adult population. While only 5% of nodules are cancerous, benign nodules can also cause complaints. It is standard of care to remove the lobe in which the nodule is present, but the use of less invasive methods, such as radiofrequency ablation (RFA), is becoming more frequent. The damaged tissue will facilitate volume reduction of the nodule and thus reduce complaints. Precise growth of RFA areas is still unknown. To better understand the ablation area growth, a clinically representative phantom has been made. The final phantom incorporates all the clinically relevant structures as well as being a flow phantom on which the heat sink effect can be studied. The phantom exists out of a PVCP neck and PAG thyroid part. To clinically validate the phantom, a radiologist performed a standard RFA procedure. The procedure was successful, however these results were unable to be analysed and clinical validation was not completed. A largely clinical accurate phantom has been created, however, further RFA experiments have to be done to clinically validate the phantom and see if the effects of RFA are comparable to those in patients.
Item Type:Essay (Bachelor)
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Biomedical Technology BSc (56226)
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