University of Twente Student Theses


A preliminary cost-effectiveness analysis of the You2yourself health monitor for earlier detection of lung cancer

Ashaqa, S. (2021) A preliminary cost-effectiveness analysis of the You2yourself health monitor for earlier detection of lung cancer.

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Abstract:Many chronic diseases are detected at an advanced stage, which potentially leads to low survival rates and higher healthcare costs. This generally happens because people visit the doctor when they have complaints and that sometimes means that the disease is already in an advanced stage. This is for example the case with lung cancer, where 50% of the cases are detected at stage IV. In order to detect diseases at an earlier stage, the You2yourself health monitor was developed. Since this health monitor is still in its infancy, its potential cost-effectiveness is unknown. To determine the potential cost-effectiveness of the health monitor, a Markov model was developed for the disease lung cancer with a lifelong time horizon and a cycle length of 6 months. An optimistic scenario and a pessimistic scenario was developed to estimate the cost-effectiveness compared to the standard care. The outcomes were costs, quality-adjusted life years (QALYs), and life years (LY). A one-way deterministic and a probabilistic sensitivity analyses were conducted to assess the impact of uncertainty on the results. The monitoring led to an increase in costs of €10,520 in the optimistic scenario and €10,584 in the pessimistic scenario. The incremental QALYs are 0.16 in the optimistic scenario and 0.02 in the pessimistic scenario. Thus, the incremental cost-effectiveness ratios (ICER) are €67,367 and €688,388 per QALY in the optimistic and pessimistic scenario, respectively. In conclusion, the health monitor seems cost-effective in the optimistic scenario at a willingness-to-pay (WTP) of €80,000/QALY. This means that only when the health monitor detects a considerably large number of patients (80%) at stage I-II, the health monitor would seem to be cost-effective.
Item Type:Essay (Master)
Faculty:TNW: Science and Technology
Subject:50 technical science in general
Programme:Health Sciences MSc (66851)
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