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Personalized non-invasive ventilation masks for children admitted to the Paediatric Intensive Care Unit

Hovenier, Renée (2021) Personalized non-invasive ventilation masks for children admitted to the Paediatric Intensive Care Unit.

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Abstract:Background – Almost half of the children admitted to the Paediatric Intensive Care Unit (PICU) require support by means of mechanical ventilation to support acute or chronic respiratory problems. This support can be given either in an invasive (endotracheal tube) or non-invasive (ventilation mask) way. In recent years, there has been a shift from invasive to non-invasive ventilation (NIV) to overcome the drawbacks including excessive sedation, long-term lung damage, and infections. However, finding a properly fitting ventilation mask proves to be a major challenge, especially in the paediatric population. Improperly fitting masks lead to patient discomfort, high air leak percentages, and pressure sores on the face. Personalized ventilation masks, for example 3D printed interfaces, have the potential of perfect fitting, and may therefore minimize these disadvantages and improve respiratory support. Therefore, a Modular Mask for children was previously devised that can be personalized using 3D scan and printing techniques. Aim – The main research aim of this graduation project was to further develop the Modular Mask concept and to investigate its potential for NIV in children admitted to the PICU. Methods – The Modular Mask consists of three separate modules (frame, cushion, and frame ring) that can be combined into an oronasal mask. The different parts were developed during this project, including design, sizes, choice of material, and production methods. Additionally, 3D printed test head models were produced in order to test the performance of the Modular Mask (in terms of air leakage and skin pressure) in an experimental setting during a pilot study. Results – The different parts of the Modular Mask were designed in such a way that they could be assembled together into a firm and usable ventilation mask. Two different prototypes were developed and were tested in a controlled environment using the corresponding 3D head models. These tests showed the potential of the Modular Mask over commercially available alternatives. Significance – The preliminary findings suggest that using the Modular Mask for NIV in children is promising. Further optimization of the mask might even improve the results and hence treatment with NIV, but validation in a larger and broader population is needed to confirm these findings. Ultimately, the goal is to provide optimal respiratory treatment for all children by offering such an individual 3D printed mask within 24 hours after admission to the PICU.
Item Type:Essay (Master)
Clients:
Amsterdam UMC, Amsterdam, Nederland
Amsterdam UMC, Amsterdam, Nederland
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Technical Medicine MSc (60033)
Link to this item:https://purl.utwente.nl/essays/89193
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