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Validity and reconstruction of the intra-arterial blood pressure waveform measured with a catheter-manometer system in critically ill neonates

Hazeleger, L.R. (2022) Validity and reconstruction of the intra-arterial blood pressure waveform measured with a catheter-manometer system in critically ill neonates.

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Abstract:Adequate blood pressure (BP) measurement, as part of comprehensive hemodynamic monitoring, is important to assess the circulation in critically ill neonates. Continuous BP measurement via an intra-arterial catheter-manometer system (CMS) is the gold standard method in neonatal care. However, validity of these measurements may be affected by the dynamic response (DR), a characteristic of the CMS. Inadequate DR of the system may lead to under- or overestimation of BP values and changes in wave shape. The aim of this study was twofold: to assess the validity of the neonatal arterial waveform and to propose and evaluate a method for the reconstruction of distorted waveforms based on DR measurements. Dynamic response of CMS for neonatal arterial waveform measurement affects mainly wave shape. MBP measurement remains reliable. Ps and PP may be affected by inadequate dynamic response, though errors are generally not clinically relevant. From measured DR, we created a measurement-specific reconstruction method which may aid in obtaining more valid neonatal arterial pressure waveforms.
Item Type:Essay (Master)
Faculty:TNW: Science and Technology
Subject:44 medicine, 50 technical science in general
Programme:Technical Medicine MSc (60033)
Link to this item:https://purl.utwente.nl/essays/89820
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