University of Twente Student Theses
3D patient-specific lung model in 3D Slicer (Optimization of the in-house protocol for patient-specific three-dimensional lung reconstruction with open-source 3D Slicer software for preoperative planning of minimally invasive major lung surgery at Zuyderland Medical Center)
Smeets, D.A.W. and Vos, M.G.A. and Dekkers, R.M. and Wiersma, G.S. (2022) 3D patient-specific lung model in 3D Slicer (Optimization of the in-house protocol for patient-specific three-dimensional lung reconstruction with open-source 3D Slicer software for preoperative planning of minimally invasive major lung surgery at Zuyderland Medical Center).
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| Abstract: | The use of a patient-specific three-dimensional lung model of the bronchi, arteries, veins, and tumor may be beneficial for preoperative planning of uniportal video-assisted thoracoscopic segmentectomy. In this study, the in-house protocol of Zuyderland Medical Center was optimized in 3D Slicer. After determining the requirements for a patient-specific 3D lung model by a literature search and interviews, the limitations of the in-house protocol were defined using two computed tomography angiography scans. Next several semi-automatic tools were tested to improve the protocol following a literature search. Finally, the renewed protocol was validated in terms of accuracy by comparing it to a reference (manually segmented model) and in terms of usability and reproducibility. Overall, 11 requirements for patient-specific 3D models have been listed. The available in-house protocol demonstrated problems with the distinction between arteries and veins, accidental over-segmentation due to unclear boundaries (leakage), and too deep in the periphery segmented models. These limitation were successfully addressed by the use of the semi-automatic 3D slicer tools.In terms of anatomical accuracy and reproducibility, the renewed protocol resulted in lower margin errors, thus higher accuracy, and was reproducible by a technical physician. The model fulfills 10 of the 11 requirements and had a hands-on time of approximately one hour. The renewed in-house protocol for patient-specific 3D lung models shows to be accurate, reproducible by a technical physician, and can be conducted within 70 minutes, thus seems to feasible for clinical use regarding preoperative planning for patients undergoing minimal invasive uniportal video-assisted pulmonary anatomical resections. |
| Item Type: | Essay (Bachelor) |
| Clients: | Zuyderland Medisch Centrum, Heerlen, Nederland |
| Faculty: | TNW: Science and Technology |
| Subject: | 44 medicine |
| Programme: | Technical Medicine BSc (50033) |
| Link to this item: | https://purl.utwente.nl/essays/90868 |
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