University of Twente Student Theses
Influence of Electrode Location, BMI, and Sex on Skin Sympathetic Nerve Activity Measurements in Healthy Subjects
Bergwerff, Niels and Dieren, Nathan van and Dolmans, Laura and Voortman, Thijs (2022) Influence of Electrode Location, BMI, and Sex on Skin Sympathetic Nerve Activity Measurements in Healthy Subjects.
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| Abstract: | Introduction: In patients with recurring arrhythmias, suppression of the sympathetic innervation of the heart by a stellate ganglion block can be a solution. The benefit of a block can be proven by a temporary block of the stellate ganglion. To make sure that the temporary block works and suppresses the sympathetic activity, the nerve activity is measured. This can be done with skin sympathetic nerve activity (SKNA) measurements. This study aimed to determine the influence of sex, Body Mass Index (BMI), and electrode location on these measurements. Materials and methods: In this study, the SKNA signals of six different lead positions were measured on 47 healthy participants. Stationary wavelet denoising was used to denoise the filtered SKNA signal. The different lead positions were compared on signal-to-noise ratios (SNR). The lead with the highest SNR was selected to test the statistical significance of the differences between BMI groups and sex. Results: The thorax leads had a better SNR than the arm leads. Thorax lead II and III were the best lead positions for measuring SKNA. BMI and sex were found to have a statistically significant difference between groups, although interactions could not be tested. Conclusion: Future research on SKNA measurements can best be done with electrode positions on the chest. There is an indication that BMI and sex have some influence on the SKNA signal. |
| Item Type: | Essay (Bachelor) |
| Clients: | Thoraxcentrum, Enschede, Netherlands |
| Faculty: | TNW: Science and Technology |
| Subject: | 44 medicine |
| Programme: | Technical Medicine BSc (50033) |
| Link to this item: | https://purl.utwente.nl/essays/90905 |
| Export this item as: | BibTeX EndNote HTML Citation Reference Manager |
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