University of Twente Student Theses
Different patterns between COPD exacerbations and comorbid flare-ups
Seuntiëns, M.M.A. (2022) Different patterns between COPD exacerbations and comorbid flare-ups.
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| Abstract: | Chronic obstructive pulmonary disease (COPD) is a progressive lung condition, characterised by exacerbations that are associated with a high morbidity, mortality and socioeconomic burden. Patients diagnosed with COPD frequently suffer from comorbidities, such as anxiety, depression, ischaemic heart disease and chronic heart failure. These comorbidities further increase morbidity, mortality and the socioeconomic burden. Therefore, it is important to be able to provide timely and appropriate treatment. However, this can be difficult as symptoms of COPD and the comorbidities are highly similar. To address this problem, it is important to understand the patterns of COPD exacerbations and flare-ups of comorbidities. Therefore, this study used data from a randomised controlled trial in which patients reported their symptoms regarding COPD and their comorbidities daily in a diary during one year of follow-up. This data were used to construct the patterns of COPD exacerbations and flare-ups of comorbidities. Based on these patterns, two groups were identified. Subsequently, these groups were compared on a variety of different baseline characteristics. The study included 61 patients, who were allocated to one of two identified groups: patients who experienced more than 50% overlap between COPD exacerbations and at least one comorbid flare-up and patients who experienced less than 50% overlap between COPD exacerbations and comorbid flare-ups. Results showed that patients who experienced more than 50% overlap between COPD exacerbations and at least one comorbid flare-up had significantly more knowledge regarding self-management practice and higher confidence in their ability to avoid and manage breathing difficulty in stressful situations. In addition, they experienced a lower feeling of control over the disease compared to patients who experienced less than 50% overlap between COPD exacerbations and comorbid flare-ups. |
| Item Type: | Essay (Bachelor) |
| Clients: | Medisch Spectrum Twente, Enschede, The Netherlands |
| Faculty: | TNW: Science and Technology |
| Subject: | 42 biology, 44 medicine |
| Programme: | Health Sciences BSc (56553) |
| Link to this item: | https://purl.utwente.nl/essays/91007 |
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