University of Twente Student Theses
The usability of PCaVision : Workflow and user interface optimization for three-dimensional multiparametric transrectal ultrasound in prostate cancer diagnostics
Went, J. (2023) The usability of PCaVision : Workflow and user interface optimization for three-dimensional multiparametric transrectal ultrasound in prostate cancer diagnostics.
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| Abstract: | Introduction: Multiparametric magnetic resonance imaging (mpMRI) is widely used as an imaging tool for prostate cancer (PCa), but it has varying sensitivity and specificity and relies on specialized radiologists. To address these limitations, 3-dimensional multiparametric ultrasound (3D mpUS) has been introduced to enhance US-based PCa diagnosis. Nevertheless, its lack of standardization and reliance on operator expertise hinder widespread adoption. This study evaluates operator dependency in the standardized 3D mpUS recording procedure and develops a PCaVision-based diagnostic workflow for cognitive and fusion-targeted biopsies. Methods: This thesis comprises two studies. The first evaluates operator dependency of the 3D mpUS recording procedure and compliance with quality standards through usability tests. The second study utilizes a design study approach, collaborating with end-users and conducting formative usability testing of the PCaVision-based diagnostic workflow and graphical user interface. Results: Usability tests showed high compliance with procedural steps and troubleshooting, with only two minor use errors. The training program effectively enhanced operator confidence, and most scans met quality standards. The second study resulted in the development of the PCaVision-based diagnostic workflow, although one design requirement was partially fulfilled. The primary workflow facilitated cognitive targeted biopsy, and the usability evaluation yielded a System Usability Score (SUS) of 60. Discussion: Both studies contributed to establishing a standardized 3D mpUS pathway using PCaVision. The standardized recording procedure proved effective, boosting operators’ confidence with minimal errors. While the training program and device’s usability may be enhanced, the procedure is easy to learn and user-friendly. The prototype of the primary PCaVision-based workflow enabled cognitive biopsies, while the fusion-targeted biopsy workflow requires further validation. Enhancements in usability are required for both training and the GUI. Overall, these results suggest that PCaVision holds promise as a valuable tool, but additional trials are necessary to validate its clinical utility and role in the diagnostic workflow of prostate cancer. Conclusion: The first study’s findings highlight operators’ successful training in the standardized 3D mpUS recording procedure, resulting in increased confidence and minimal errors. The primary PCaVision-based diagnostic workflow enables cognitive targeted biopsy, whereas the fusion-targeted biopsy workflow requires further validation. The standardization of the 3D mpUS pathway is an essential cornerstone for the future of accurate and effective PCa diagnostics. |
| Item Type: | Essay (Master) |
| Clients: | Angiogenesis Analytics, Den Bosch, Netherlands Amsterdam UMC, Amsterdam, Netherlands |
| Faculty: | TNW: Science and Technology |
| Subject: | 44 medicine |
| Programme: | Technical Medicine MSc (60033) |
| Link to this item: | https://purl.utwente.nl/essays/95049 |
| Export this item as: | BibTeX EndNote HTML Citation Reference Manager |
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