University of Twente Student Theses


Onderzoek naar het driftartefact bij FFR-metingen in een coronair fantoom

Bergen, L.C.M. van and Hoenderboom, L. and Kuper, O.S. (2023) Onderzoek naar het driftartefact bij FFR-metingen in een coronair fantoom.

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Abstract:Fractional Flow Reserve (FFR) is a widely used method for assessing the severity of stenosis by measuring pressure ratio before and after stenosis. FFR is utilized in Isala Zwolle and is considered a reliable method to characterize stenosis. However, artifacts can undermine the accuracy of these measurements. In particular, the so-called drift artifacts where the co-registered pressures no longer match after the measurement. This leads to unreliable results, prolonged procedures, and thus a higher risk of complications. Consequently, studying the occurrence of drift artifacts is crucial to help prevent such issues. Although the exact causes have yet to be identified, several studies explore potential factors that might influence the frequency of these artifacts. For instance, calibration time, temperature and flow are thought to affect how frequently drift occurs. A phantom was made to test a couple of these parameters and to see if connections could be found between certain parameters and drift. Results of this study indicate that Abbott's PressureWire X is more reliable than Philips' Omniwire as it demonstrated fewer drift artifacts. Further study is recommended to identify the underlying causes of these observed differences.
Item Type:Essay (Bachelor)
Isala, Zwolle, Netherlands
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Technical Medicine BSc (50033)
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