University of Twente Student Theses
The Respiro project : Evaluation of the Respiro® measurements of peak inspiratory flow, duration of inhalation and orientation in a clinical setting
Moussally, Naya (2023) The Respiro project : Evaluation of the Respiro® measurements of peak inspiratory flow, duration of inhalation and orientation in a clinical setting.
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| Abstract: | This research study investigated the performance of the Respiro® Nexthaler add-on device in assessing inhalation parameters including peak inspiratory flow, inhalation duration, and inhalation orientation. The study employed an adult population trained with a trainer inhaler in a real-world setting. A total of 11 healthy volunteers, diverse in terms of age and gender, were included in the study. The participants were trained using the InCheck Dial inhaler, while the measurements were captured using the Respiro® Nexthaler add-on device. The device successfully captured the correct inhalation orientation in 81% of instances, and the correct inhalation duration in 87% of cases. These findings were validated through the McNemar test, indicating a non-significant difference in device performance for capturing horizontal and vertical orientations, and a significant difference in capturing inhalation durations ≤1.4 and >1.4. Furthermore, a strong positive intra-class correlation coefficient of 0.94 was found between the duration captured with a stopwatch and the duration captured with the Respiro® device. In terms of flow rates, the Respiro® device demonstrated varying performance. For the trained 35 L/min flow rate, the device captured a significantly lower flow rate, while for the trained 60 L/min flow rate, the device captured a significantly higher flow rate. However, a combined t-test revealed no significant difference between all inhalations during training and all inhalations recorded by the Respiro® device, regardless of the specific flow rates. The results of this study affirm the potential utility of the Respiro® Nexthaler add-on device in accurately capturing inhalation parameters in clinical practice. This tool can potentially optimize medication adherence and enhance the management of respiratory conditions. Future research should aim to address the observed discrepancies in flow rate measurements and continue to improve the capabilities of such devices. |
| Item Type: | Essay (Bachelor) |
| Clients: | Medisch Spectrum Twente, Enschede, Netherlands |
| Faculty: | TNW: Science and Technology |
| Subject: | 44 medicine |
| Programme: | Health Sciences BSc (56553) |
| Link to this item: | https://purl.utwente.nl/essays/95284 |
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