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Diaphragm thickness measuring tool for ultrasound imaging, An experimental study investigating the diaphragm thickness using a newly developed diaphragm thickness measuring tool

Laarman, K. and Laat, S. de and Nabben, T. and Zomer, F. (2023) Diaphragm thickness measuring tool for ultrasound imaging, An experimental study investigating the diaphragm thickness using a newly developed diaphragm thickness measuring tool.

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Abstract:A possible relationship between the progression of ventilator induced diaphragm dysfunction (VIDD) and diaphragm thickness (Td) in mechanically ventilated children is still unproven. The purpose of this study was to create a reliable and validated tool, which measures the Td in ultrasound (US) images automatically over time. The study population consisted of patients aged 0-5 years who were expected to be mechanically ventilated for more than 24 hours at the pediatric intensive care unit (PICU) of University Medical Centre Groningen (UMCG). US images were made by technical physicians of the UMCG and sorted on quality. A tool was made to analyse the US images by loading a DICOM file, extracting necessary information, resizing and denoising of the US images, and displaying them in a "super slider" interface. The tool provides an automated measurement of the Td in a generated interactive graph. The performance of the tool was evaluated and statistically compared to manual measurements, providing insights into its reliability and validity. Manual measurements conducted by the researcher were compared to a technical physician to check the reliability and validity of our own measurements. Manual Td measurements and frame number selection by the researcher showed excellent agreement and correlation (ICC: 0,948; ICC: 0,999) compared to the technical physician. The comparison between the researcher and the results of the tool showed excellent agreement and correlation of the Td measurements (ICC: 0,948) and frame number selection (ICC: 0,994). The calculated TF resulting from these measurements showed moderate agreement and correlation (ICC: 0,675). The influence of manually selected inputs on Td were tested using the tool. The results showed that adjusting these inputs led to variations in Td. The researcher’s measurements were used without effecting the reliability and validity of the study. To measure the Td, the tool showed perfect reliability and excellent validity, meaning that when the US images meet the inclusion criteria, the tool is capable of measuring the Td.
Item Type:Essay (Bachelor)
Clients:
UMCG, Groningen, The Netherlands
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Technical Medicine BSc (50033)
Link to this item:https://purl.utwente.nl/essays/96008
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