University of Twente Student Theses

A Longitudinal Cohort Study Exploring the Bidirectional Lagged Relationship Between Fatigue and Depressive Symptoms Among Hospitalised COVID-19 Patients

Gehling, Simon (2023) A Longitudinal Cohort Study Exploring the Bidirectional Lagged Relationship Between Fatigue and Depressive Symptoms Among Hospitalised COVID-19 Patients.

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Full Text Status:	Access to this publication is restricted
Embargo date:	26 July 2028
Abstract:	Since its outbreak in December 2019, the acute coronavirus disease 2019 (COVID 19) has pandemically affected the world. However, today’s literature does not provide clear evidence about different post COVI symptom trajectories nor their interactions, specifically between fatigue and depressive symptoms. Therefore, this study investigated the individual symptom trajectories as well as the bidirectional lagged relationship between fatigue and depressive symptoms over a period of 12 mo nths among individuals that were hospitalised due to a COVID 19 infection. In addition, this study further aimed to clarify contradicting findings among sociodemographic and behavioural factors and explored the potential moderation of these factors on the bidirectional lagged relationships. By applying a non probability sampling method, this study recruited 735 participants. Fatigue was assessed by the Short Fatigue Questionnaire (SFQ), while depressive symptoms were assessed by a mental component summary (MCS) derived from the Short Form Health Survey (SF 36). The two symptom trajectories were analysed using Pearson correlations and repeated measure ANOVA. The symptoms correlation was analysed by applying Pearson correlation per measurement point. The bidi rectional lagged relationship was analysed using a cross lagged panel analysis, including linear regression and partial correlation analysis. Group differences were analysed using independent sample t tests or one way ANOVA, while separate linear mixed mod els (LMM) were applied to analyse the moderation of sociodemographic and behavioural factors. According to the results, this study demonstrated that fatigue and depressive symptoms improved significantly over time, with the most substantial decrease befor e 6 months after hospital discharge. Furthermore, this study found that both symptoms were consistently correlated over time, but no convincing evidence for a bidirectional relationship between the two symptoms was found. Even though this study did find si gnificant group differences, especially for sociodemographic factors, only a moderation was found in the lagged relationship between depressive symptoms (independent variable) and fatigue (dependent variable).
Item Type:	Essay (Master)
Faculty:	BMS: Behavioural, Management and Social Sciences
Subject:	77 psychology
Programme:	Psychology MSc (66604)
Link to this item:	https://purl.utwente.nl/essays/96857
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