University of Twente Student Theses
Imaging Behind the Plaque - Improved Blood Flow Imaging Using ISAAC: an Iterative Scheme for Active Attenuation Correction.
Plomp, Jelle (2023) Imaging Behind the Plaque - Improved Blood Flow Imaging Using ISAAC: an Iterative Scheme for Active Attenuation Correction.
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| Abstract: | Blood flow quantification using high frame rate (HFR), contrast enhanced ultrasound (CEUS) followed by particle image velocimetry (PIV), allows studying flow phenomena in stenosed and stented arteries. However, attenuation of ultrasound caused by calcified atherosclerotic plaque limits the signal strength received from the contrast agents and leads to incomplete flow quantification. The current paper therefore develops a method to enhance the signal strength by locally increasing the acoustic pressure during the HFR measurement. Evaluation in an in vitro setup shows that errors in PIV-derived velocities up to 65% in the acoustic shadow region can be reduced to less than 10% using the compensation strategy. Even in cases where the attenuation cannot be fully compensated for, velocity estimates are still improved using the proposed compensation strategy. The method is therefore expected to improve the accuracy of flow measurements in acoustic shadow regions when applied in vivo. |
| Item Type: | Essay (Master) |
| Faculty: | EEMCS: Electrical Engineering, Mathematics and Computer Science |
| Subject: | 30 exact sciences in general, 33 physics, 44 medicine, 53 electrotechnology |
| Programme: | Electrical Engineering MSc (60353) |
| Link to this item: | https://purl.utwente.nl/essays/97808 |
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