University of Twente Student Theses


The POLYP-study: Guideline Adherence Leads to Overtreatment of Gallbladder Polyps

Wietsma, M.F.T. (2023) The POLYP-study: Guideline Adherence Leads to Overtreatment of Gallbladder Polyps.

Full text not available from this repository.

Full Text Status:Access to this publication is restricted
Embargo date:31 December 2024
Abstract:Gallbladder (GB) polyps are common but risk of malignancy remains low. Management guidelines rely primarily on polyp size as an indication for cholecystectomy. The surgical threshold with polyps >1 cm remains controversial and is proven to be insufficient. Guideline adherence remains sub-optimal according to the 2017 and 2021 guidelines; only 48.4% and 59.7% of patients reaching indication for cholecystectomy, underwent surgical treatment. Conservative adherence was even worse, with adequate follow-up duration after first visit in only 38.9% and 42.6% of patients following 2017 and 2021 guidelines. While guideline adherence remains sub-optimal, strict adherence to the guideline may paradoxically result in overtreatment and futile cholecystectomies. The aggressive management of small GB polyps leads to excessive costs and unnecessary follow-up imaging, whereas the malignant potential of these polyps remains very small. This study underscores the importance of refining pre-operative patient selection and identification of potentially neoplastic polyps
Item Type:Essay (Master)
Faculty:TNW: Science and Technology
Subject:44 medicine
Programme:Health Sciences MSc (66851)
Link to this item:
Export this item as:BibTeX
HTML Citation
Reference Manager


Repository Staff Only: item control page