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Towards real-time endoscopic verification of lung lesion by bio-impedance measurements to improve biopsy accuracy

Langerak, N.C. (2021) Towards real-time endoscopic verification of lung lesion by bio-impedance measurements to improve biopsy accuracy.

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Full Text Status:Access to this publication is restricted
Embargo date:1 January 2040
Abstract:Lung cancer is the cancer with the highest mortality in the Netherlands. 80% of all patients diagnosed with lung cancer die within five years. One of the main reasons for this high mortality is the advanced stage of disease at diagnosis. When a pulmonary lesion is found on computed tomography, pathological tissue is preferably obtained through minimally invasive procedures. However, small lesion sizes in peripheral lung tissue (where there is no video-endoscopic guidance) limit the ability to accurately obtain tissue sample of the pathology of interest. A technique that enables real-time tissue verification on a local level before taking a biopsy is therefore an important addition. One of the possible techniques is electrical impedance spectroscopy (EIS). It is thought that the spectrum for healthy, malignant and benign tissue is different due to differences in cell size and shape and differences in orientation and structure of cell membranes.
Item Type:Essay (Master)
Faculty:TNW: Science and Technology
Subject:42 biology, 44 medicine, 50 technical science in general, 53 electrotechnology
Programme:Technical Medicine MSc (60033)
Link to this item:http://purl.utwente.nl/essays/85937
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