University of Twente Student Theses
Analysis of the electrophysiological data acquired on the PhysioHeartTM platform : (ex vivo beating heart)
Hoek, S. van der (2024) Analysis of the electrophysiological data acquired on the PhysioHeartTM platform : (ex vivo beating heart).
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| Abstract: | Cardiovascular diseases require effective preventive strategies and minimally invasive interventions. LifeTec Group B.V. developed the PhysioHeartTM platform using slaughterhouse hearts to simulate cardiac conditions. Enhanced for MRI-guided therapies, the platform aims for real-time treatment visualization. This research compares the 2-chamber and 4-chamber configurations to determine the better setup. Ion imbalances were induced to assess their impact on electrophysiology and mechanical activation and local stimulation was applied, to show the possibility of detecting arrhythmic substrates. Results showed that local activation can be effectively measured through grid pacing. The 2-chamber setup offered more stability and consistent results. Electrophysiology and mechanical activation patterns combined effectively detected ion imbalances. |
| Item Type: | Essay (Master) |
| Clients: | LifeTec Group B.V., Eindhoven, The Netherlands |
| Faculty: | ET: Engineering Technology |
| Subject: | 52 mechanical engineering |
| Programme: | Mechanical Engineering MSc (60439) |
| Link to this item: | https://purl.utwente.nl/essays/101446 |
| Export this item as: | BibTeX EndNote HTML Citation Reference Manager |
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