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Design and validation of an MRI compatible anthropomorphic liver phantom

Zacharias, J.S. (2024) Design and validation of an MRI compatible anthropomorphic liver phantom.

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Abstract:Respiratory motion poses significant challenges in medical imaging and procedures involving the liver, affecting precision in needle insertions and increasing risks of tissue trauma. Current liver phantoms can simulate respiratory motion but often lack realism, particularly in MRI-compatible environments. This thesis introduces an anthropomorphic liver phantom capable of replicating Superior-Inferior (SI) and Anterior-Posterior (AP) respiratory movements. Actuated using MRI-compatible pneumatic origami actuators, the phantom mimics natural breathing patterns cost-effectively and accurately. Housed within a 3D-printed ribcage, the soft rubber liver phantom recreates realistic anatomical constraints. The system uses an open-loop Arduino control mechanism to simulate breathing, with potential for future closed-loop integration for enhanced precision. Modular and MRI-compatible, the design allows for easy maintenance and adaptability. Validation demonstrated controlled motion in both SI and AP directions, proving its effectiveness in simulating respiratory motion for clinical contexts. This innovative design contributes to safer and more effective liver procedures by improving the realism and functionality of liver phantoms. Its modularity and adaptability support further advancements, offering a step forward in medical imaging and treatment.
Item Type:Essay (Master)
Faculty:EEMCS: Electrical Engineering, Mathematics and Computer Science
Subject:44 medicine, 52 mechanical engineering
Programme:Systems and Control MSc (60359)
Link to this item:https://purl.utwente.nl/essays/104760
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