University of Twente Student Theses
Analysis of flow in stented aneurysm
Ong, Gabriela M. (2018) Analysis of flow in stented aneurysm.
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| Abstract: | Among the challenges in the simulation of haemodynamics in the human brain is the problem of connecting the raw data from medical imagery to a quantitative, patient-specific prediction of the flow in order to provide information assisting practitioners when deciding on a treatment. In this study a sequence of steps is presented to facilitate such connection, focusing on an endovascular treatment known as flow-diverter stenting. Starting from DICOM data, the format changes and preparations based on Horos and Blender are described, as pre-cursors to an immersed boundary (IB) representation of the geometry. On the IB representation, a fluid mechanics analysis within the CFD toolbox OpenFOAM is done, providing both qualitative and quantitative descriptions of the flow. This sequence of steps is discussed and illustrated for flow in a model geometry with the typology of a side-wall aneurysm, under steady-state and pulsating flow conditions. The flow diverting effect of two different stents is presented, showing a significant blocking of flow from entering the aneurysm sac after stent placement. Under suitable spatial resolution conditions accurate results are obtained and we observe that both a fine-mesh flow diverter and an eCLIPS device perform virtually identically in terms of almost completely halting the flow in the aneurysm sac. A slight preference for an eCLIPS can be motivated, showing a more uniform flow blocking also in the immediate vicinity of the device, combined with more flexibility of merging it with the diseased vessel. |
| Item Type: | Essay (Master) |
| Faculty: | EEMCS: Electrical Engineering, Mathematics and Computer Science |
| Subject: | 31 mathematics |
| Programme: | Applied Mathematics MSc (60348) |
| Link to this item: | https://purl.utwente.nl/essays/76213 |
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