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Prognostic value of 18FFDG PET radiomics to detect peritoneal and distant metastases in locally advanced gastric cancer - a side-study of the prospective multicenter PLASTIC trial
Pullen, C.E. (2022) Prognostic value of 18FFDG PET radiomics to detect peritoneal and distant metastases in locally advanced gastric cancer - a side-study of the prospective multicenter PLASTIC trial.
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| Abstract: | Patients with locally advanced gastric cancer have a five-year survival rate of 36-45% after curatively intended D2-gastrectomy combined with perioperative chemotherapy. This relatively poor survival is mainly due to the recurrence of the disease. This study aimed to improve the detection of distant and peritoneal metastases on [18F]FDG-PET images in patients with advanced gastric cancer by extracting and analysing imaging features from these images, known as radiomics. Three predictive models were developed to determine the added value of implementing radiomics: with clinical variables only, radiomic features only, and a combination of both. [18F]FDG-PET-based radiomics showed no additional value in predicting distant nor peritoneal metastases in locally advanced gastric cancer patients. |
| Item Type: | Essay (Master) |
| Faculty: | TNW: Science and Technology |
| Subject: | 44 medicine, 50 technical science in general |
| Programme: | Biomedical Engineering MSc (66226) |
| Link to this item: | https://purl.utwente.nl/essays/93901 |
| Export this item as: | BibTeX EndNote HTML Citation Reference Manager |
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