University of Twente Student Theses


Pharmaceutical Cold Supply Chain Management Considering Medication Synchronization and Different Delivery Modes

Potters, E.M. (2023) Pharmaceutical Cold Supply Chain Management Considering Medication Synchronization and Different Delivery Modes.

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Embargo date:25 July 2024
Abstract:Last-mile logistics in the healthcare supply chain is becoming increasingly important, especially in pharmacies where medication delivery to patients’ homes is becoming prevalent. Therefore, this paper proposes a mathematical model for the last-mile logistics of the pharmaceutical supply chain and optimizes a pharmacy’s logistical financial results while considering medication synchronization, different delivery modes, and temperature requirements. In this research, we create a Mixed Integer Linear Programming (MILP) model to find optimal solutions regarding the number of order batches, the composition of these batches, and the number of staff related to the preparation of the order batches. We create a case study by gathering, preparing, processing, and analyzing the data associated with an outpatient pharmacy of a Dutch hospital. Our results show that our optimal solution increases the pharmacy’s logistical results by 34 percent. Besides, we propose other model variations and perform extensive scenario analysis to provide managerial insights useful for various pharmacies and distributors in the last step of cold supply chains. In particular, our scenario analysis of these results suggests that improving medication synchronization can significantly enhance the pharmacy’s financial results. Furthermore, the model proves to be a tool for assessing multiple sets of scenarios relevant to the pharmacy.
Item Type:Essay (Master)
Sint Maartenskliniek, Nijmegen, Netherlands
Faculty:BMS: Behavioural, Management and Social Sciences
Subject:31 mathematics, 58 process technology, 85 business administration, organizational science
Programme:Industrial Engineering and Management MSc (60029)
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